Alli (Orlistat 60mg)

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Alli can help you lose weight by reducing the amount of fat you absorb during digestion.

Alli is clinically proven for weight loss

What is Alli?

Alli is a clinically proven weight loss aid used to treat adults who are overweight and have a BMI of 28 or higher. Alli is designed to help you to lose more weight than by dieting alone as long as you follow a reduced calorie, low fat diet and exercise regularly.

It contains the active ingredient orlistat which is the only medicine licensed in the EU for weight loss.

Alli is not an appetite suppressant, stimulant, fat blocker, or a pill with magical properties. You still have to eat a healthy low calorie, lower fat diet and exercise regularly, but Alli helps you lose weight faster.

Alli Weight Loss Plan

How does Alli work?

Unlike other over the counter slimming pills, Alli works in a unique way to target the fat in the digestive system. Its active ingredient, orlistat, attaches to the enzyme lipase that breaks down the fat from a meal, effectively preventing it from digesting fat.

It stops about a quarter of fat from your diet from being absorbed and this fat will pass out of your body in your stools.

As a result, the fat cannot go through the gut lining and be stored. The fat just passes through the body and is excreted so calories do not turn into extra weight.

How effective is Alli?

For every 2kg you lose through dieting and exercise, Alli diet pills can help you lose an additional 1kg. It has been clinically proven to help you lose 50% more weight than dieting alone.

In a clinical study, visceral fat was reduced in over 70% of Alli users who followed a reduced calorie, lower-fat diet.

How do I take Alli?

The Alli tablets should be swallowed whole with water three times day during meal times. It can be taken one hour before, during or an hour after the meal to be effective. Don’t take it if you are having a meal without any fat or if you skip a meal. Also, you should not take the medication more than three times a day.

Since Alli affects how the body absorbs different foods, your body may struggle to extract adequate amounts of certain nutrients from your regular diet alone. You should supplement your diet with a multivitamin specifically designed to replenish the vital vitamins and minerals lost. We recommended the OneVit Complete multivitamin, a daily supplement that rebalances a wide range of important micronutrients, such as vitamins A,D, E and K.

Adding Alli to a reduced calorie, lower-fat diet can boost weight loss by 50%

Can I take Alli?

Alli is only licensed to adults with a BMI of 28 and over and should be taken in conjunction with a healthy low calorie diet. Alli does not require a fat-free diet, just reduced fat. In fact, fat is an important part of a healthy diet in moderate amounts. It helps the body absorb vitamins and other essential functions in the body.

Body Mass Index (BMI) and Alli

Alli may be suitable if you have a body mass index (BMI) of over 28. You can quickly calculate your BMI by entering your height and weight into our BMI calculator.

How does it help lose weight I already have?

Without the additional fat and calories, your body needs to get the energy from someplace else. Luckily, it has all that stored fat that it can burn for energy to keep you going through your working day and any strenuous Zumba-like activity. With healthy eating, physical exercise and Alli as your aid in fat aversion, weight loss can be boosted by 50%.

How fast does Alli work?

Alli is the only clinically proven weight loss medication in the UK. Alli starts to work as soon as you take it to decrease the amount of fat absorbed into your body and you can see the results depending on your diet and exercise.

Side Effects

The most common side effects of Alli (Orlistat 60mg) include:

  • oily rectal discharge
  • passing gas with oily discharge
  • urgent need to have a bowel movement
  • oily or fatty stools
  • increased number of bowel movements
  • being unable to control your bowel movements

All medications can cause side effects. You may not experience any of them. The majority of the common side effects experienced with Alli are related to the way it works in your digestive system. These side effects are usually mild, occur at the beginning of treatment, and particularly after high fat meals. Normally these symptoms will subside as you continue treatment and follow your recommended diet.

The most common side effects of Alli, which may affect more than 1 in 10 people include headache, abdominal pain or discomfort, urgent or increased need to open the bowels, wind, oily discharge or oily/fatty stools.

 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Written and reviewed by our qualified team

GPhC Number: 2088658

Carolina Goncalves

Authored by:

Carolina Goncalves


GPhC Number: 2225869

Rehma Gill

Reviewed by:

Rehma Gill


Find out more about how we ensure the accuracy of our content with our content guidelines.

Content last updated: 08 Aug 2023

Alli Reviews

9.4/ 10
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Based on 2,127 independent customer reviews taken by Feefo (see all Feefo Reviews), Google and Trustpilot (see all Trustpilot Reviews).

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"Excellent service by Pharmica"

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"Delivery was very quick and had no issues with the whole process"

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"Straight forward and efficient."

Product Review:

"Used along with watching what you're eating, Ali does get rid of extra fats you have consumed and I think does aid weight loss."

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"The ordering process was easy & straight forward. My order was delivered the following day & was well packaged."

(read on Feefo)
"Fast delivery"

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"Lost half a stone in a week on these"

Service Review:

"Fast delivery good prices would order again"

(read on Feefo)
"Quick delivery"

Product Review:

"Appears to be aiding weight loss in addition to healthy diet"

Service Review:

"Quick delivery and no problems with my order"

(read on Feefo)
"Excellent service"

Product Review:

"Product ok but you still need to diet! :-)"

Service Review:

"Excellent service, quick and efficient."

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"great company"

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"A product that really works"

Service Review:

"Good quick service and good price"

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"Economical and quick delivery of order."

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"Does what it says on the box."

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"Quick dispatch and delivery."

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"Fantastic service"

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"Great weight loss tablets. Will continue to buy for as long as required"

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"My purchase was easy to do and was delivered next day. No waiting around for it to arrive."

(read on Feefo)
"Excellent service"

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Service Review:

"Fast service and delivery"

(read on Feefo)
"Excellent service."

Product Review:

"Still using the product, should see results hopefully in a few months."

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"Timely delivery of products, sealed and totally legitimate. Good customer service and packaging."

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