Desogestrel

Progestogen-only Contraceptive Pill (Mini Pill) Containing Desogestrel

Desogestrel
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Desogestrel is a POP or mini pill containing desogestrel, a synthetic form of progestogen that is up to 99% effective at preventing pregnancy.

Pack size: 28 Tablets (4-Week Supply)

Desogestrel Product Information

Desogestrel is a generic progestogen-only contraceptive pill (mini pill), containing the active ingredient desogestrel. It is formulated to be taken daily.

Desogestrel differs from other progestogen-only contraceptive pills in that it prevents eggs from maturing in the body, rather than blocking sperm from reaching the egg.

Desogestrel is used by adult women to prevent pregnancy. It contains desogestrel, a synthetic form of the female sex hormone progesterone, which is 99% effective at preventing pregnancy if used correctly.

Desogestrel works by preventing the ripening of the egg in the female body. This differentiates Desogestrel from other progestogen-only pills, which focus more on preventing sperm from reaching and fertilising eggs, as opposed to preventing eggs from maturing.

Desogestrel is immediately effective if taken from the first day of the menstrual cycle continuously with no breaks between packs. If Desogestrel is started at any other time during the menstrual cycle, it is recommended to use a barrier contraceptive method, such as condoms, for the first seven days of taking Desogestrel. This can help maximise the chance of preventing pregnancy.

Take one Desogestrel pill per day at the same time each day. Each pack contains 28 tablets, and a new pack should be started immediately after finishing the previous one without any breaks. This continuous intake maximises the effectiveness of Desogestrel at preventing pregnancy.

Desogestrel is 99% effective at preventing pregnancy if taken correctly (refer to the patient information leaflet for directions for use). Desogestrel may be more effective at preventing pregnancy than other progestogen-only pills due to its unique mechanism of action, which prevents eggs from ripening in the female body. The effectiveness of Desogestrel may be reduced if doses are missed.

Desogestrel is suitable for adult women, especially for those who may not be able to take synthetic oestrogen. However, Desogestrel should not be taken by individuals who have had certain types of cancer, severe liver disease, or thrombosis, or those who are allergic to any of its ingredients.

Desogestrel is also suitable for breastfeeding mothers. 

Desogestrel is the generic version of Cerazette and Cerelle. All three brands of contraceptive pills are medically identical, as they all contain the same active ingredient, desogestrel, which is a synthetic form of progesterone.

Desogestrel FAQs

If you forget to take a dose of Desogestrel, and it has been more than 12 hours since the missed dose, continue taking the pill as normal at your usual time. Use barrier contraception (such as condoms) for the next 7 days since the missed dose to help prevent pregnancy. If it has been less than 12 hours since the missed dose, you may not need to use barrier contraception in addition to taking Desogestrel, as the medication is likely to remain effective as if a dose was not missed.

Desogestrel does not stop periods and is not a period delay treatment, but it can alter menstrual bleeding patterns. Some users may experience infrequent or no bleeding at all, while others may experience irregular bleeding. The time at which this occurs can vary from person to person.

Weight gain may cause weight gain in some women, depending on individual physiological responses to the hormone. Please consult your doctor or GP if you experience weight gain while taking Desogestrel.

You can buy Desogestrel from Pharmica after completing a free online consultation to determine treatment suitability.

Desogestrel Overview

Desogestrel side effects

Like any medication, Desogestrel can result in some side effects, which vary from person to person.

Some of the more common and less serious side effects of Desogestrel (which may affect 0.1% of women) include:

  • Spotting and light bleeding
  • Missed periods
  • Mood changes
  • Decreased sexual drive (libido)
  • Headaches
  • Nausea
  • Acne
  • Breast pain and/or discomfort
  • Weight changes

Uncommon side effects of Desogestrel, which may affect up to 0.01% of women, include:

  • Vaginal infection
  • Vomiting
  • Hair loss
  • Painful menstruation
  • The development of an ovarian cyst
  • Fatigue

Some of the rarer and more serious side effects of Desogestrel, which may affect up to 0.001% of women, include:

  • Symptoms of angioedema, such as:
    • A swollen face, tongue, or neck
    • Difficulty swallowing
    • Difficulty breathing
  • Prolonged or heavy bleeding (if this occurs, consult with a doctor immediately)
  • Rash
  • Hives
  • Painful bluish-red lumps on the skin (erythema nodosum)

If you experience any of the side effects above, particularly the more serious side effects, contact a GP or doctor immediately. Please read the patient information leaflet for further information.

Written and reviewed by our qualified team

GPhC Number: 2088658

Carolina Goncalves
Authored by: Carolina Goncalves Superintendent
Pharmacist

GPhC Number: 2225869

Rehma Gill
Reviewed by: Rehma Gill Pharmacy
Manager

Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 21 Jan 2025

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