Differin (Adapalene) 0.1%

Differin (Adapalene) Is A Powerful, Highly Effective Acne Treatment

Differin (Adapalene) 0.1%
Price Checker
Lowest price guarantee Includes FREE private prescription
Get started now
Free shipping on all orders over £50

Receive it:
Order within:

  • MHRA-approved medication From our UK registered pharmacy
  • Join over 1.35 million customers Excellent rated customer service
  • Private and confidential Discreet packaging and payment
  • Discreet next day delivery Quickly & discreetly packaged
Differin (Adapalene) gel and cream are effective acne treatments, clinically proven to clear and prevent mild to moderate acne.
Cetaphil Gentle Skin Cleanser
Cetaphil Gentle Cleanser - 236ml Only £8.99! Add to Cart
Cetaphil Gentle Skin Cleanser
Cetaphil Gentle Cleanser - 473ml Only £14.99! Add to Cart
Cetaphil Gentle Exfoliating Cleanser
Cetaphil Exfoliating Cleanser - 178ml Only £11.99! Add to Cart

Buy Differin (Adapalene) 0.1% Online

What is Differin and how does it help to clear my acne?

Differin contains the active ingredient Retinoid Adapalene, which is clinically proven to clear and prevent mild to moderate acne. Adapalene is an anti-inflammatory medicine, highly effective at reducing the formation of whiteheads and blackheads on the outer layer of skin. Differin is non-comedogenic and fragrance-free; it actively helps to prevent breakouts, whiteheads, blackheads, clogged pores and blemishes. Differin is ideal for daily use in either a gel or cream to remove acne and return skin back to its healthy tone and texture.

What are the benefits of Differin (Adapalene) gel and cream?

  • Contains Retinoid Adapalene to actively clear acne.
  • Prevents breakouts, whiteheads, blackheads, clogged pores and blemishes.
  • Restores skin tone and texture.
  • Non-comedogenic.
  • Fragrance-free.

How long does it take to start seeing results while using Differin?

As with all acne medication, results may not be seen before 12 weeks. However, in many cases, results can be observed following continued use during a 12 week period. It is important to use Differin consistently and continually to ensure you get the best results.

How do I use Differin (Adapalene) gel and cream?

Apply a thin layer of Differin cream or gel once a day, all over your face. For practicality, application before bedtime is recommended.

Be careful not to apply Differin to sensitive areas such as the mouth, nostrils or eyes. Take care to wash your hands before and after use. Do not apply Differin to broken skin. Temporary skin irritation (retinization) can occur while adjusting to the active ingredient, this should subside by week 4. Always read the patient information leaflet before use and seek further professional advice if necessary.

 Information Leaflet

Always read the patient information leaflet before commencing treatment.

Written and reviewed by our qualified team

GPhC Number: 2088658

Carolina Goncalves
Authored by: Carolina Goncalves Superintendent

GPhC Number: 2225869

Rehma Gill
Reviewed by: Rehma Gill Pharmacy

Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 20 Mar 2023

Differin Reviews

9.8/ 10
Truspilot logo
Google logo
Feefo logo

Based on 166 independent customer reviews taken by Feefo (see all Feefo Reviews), Google
and Trustpilot (see all Trustpilot Reviews).

Reviewed on Feefo
"Great service"

Product Review:

I have only been using a few weeks so I'm not expecting dramatic results as yet, but so far I haven't had any irritation or drying effect.

Service Review:

Easy to order following a few brief questions, and delivered quickly

Reviewed on Trustpilot
"Swift delivery & always convenient"

Product Review:


Service Review:

Swift delivery & always convenient. Thankyou very much

Reviewed on Trustpilot
"Better skin better you ."

Product Review:

Since I have been using differin , I have had so many complements on my skin .

Service Review:

Since I have been using my face cream , I am getting so many complements on my skin .

Reviewed on Trustpilot
"Dream team "

Product Review:

I haven't been using it that long , but I'm impressed so far .

Service Review:

I put in what I need and they are so helpful , my product comes very quick and no fussing , love it x

Reviewed on Trustpilot
"Great company"

Product Review:

Works really well. Came recommended

Service Review:

Great company. Reliable. Fast delivery

Reviewed on Feefo

Product Review:


Reviewed on Feefo
"Reliable, easy and great."

Product Review:

Great product, sent quickly. Professional and reliable.

Service Review:

Fabulous, v appreciated.

Reviewed on Trustpilot
"They are very helpful "

Product Review:

It is very easy to apply , it is none greasy.

Service Review:

They are very helpful , and it is very quick and easy to order .

Reviewed on Feefo
"Very speedy delivery service"

Product Review:

Brilliant can easily recommend

Service Review:

Absolutely brilliant service very fast delivery prompt and organised.
Thankyou for a great price and service and your loyalty points are a grear idea

Reviewed on Trustpilot
"Great retinol product"

Product Review:

Great product. Effective and not too harsh on the skin. Highly recommended.

Service Review:

Great retinol product. Effective but not too harsh. Highly recommended.

Discreet service

With our discreet packaging you can order in confidence.

We never use our brand name on bills, delivery papers or your bank statement.

All our packages are completely plain, without any details of what’s inside or who has sent it.

Estimated delivery

Signed For 1st Class

£2.90 - Saturday 20 July

Collect from your Post Office

£3.95 - Saturday 20 July

Special Delivery 1pm Guaranteed

£5.95 - Saturday 20 July by 1pm

Special Delivery 9am Guaranteed

£13.95 - Saturday 20 July by 9am

Same Day Delivery

from £4.95 - Friday 19 July

How does it work?

How it works - Consultation

Online consultation

Complete a short questionnaire to check your eligibility for treatment

Refer a friend step 1

Choose a treatment

Select the treatment or medication you need from leading brands

How it works - Delivery

Express delivery

Medication is dispensed and delivered to your home or work

Related articles

Discover scientifically proven tips on how to care for acne-prone skin and understand key facts about acne in this comprehensive guide from our experts.
Find out how to get clear skin by knowing your skin type and implementing these essential skin care tips.
As the body’s largest organ, the skin is constantly exposed to the elements. It pays to establish a consistent daily skincare routine that’s right for your particular skin type, and to treat outbreaks of acne and eczema as soon as they appear.